pharmacokinetic comparison of loratadin self-emulsifying drug delivery system with its conventional oral solution in rat

In vivo Evaluation of Self Emulsifying Drug Delivery System for Oral Delivery of Nevirapine

Nevirapine is a highly lipophilic and water insoluble non-nucleoside reverse transcriptase inhibitor used for the treatment of HIV-1 infection. Lymphoid tissue constitutes the major reservoir of HIV virus and infected cells in HIV-infected patients. Self-emulsifying drug delivery system, using long chain triglycerides, is a popular carrier of drugs due to their ability to transport lipophilic d...

Design, Development and In Vitro Characterization of Self Emulsifying Drug Delivery System for Irbesartan

The objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (SEDDS) in order to enhance the dissolution rate of poorly soluble Irbesartan (IBS) by SEDDS. Pseudoternary phase diagrams were constructed to identify the self emulsifying region....

Recent advances in self emulsifying drug delivery system - A review

Self-emulsifying drug delivery systems (SEDDS) are usually used to improve the bioavailability of hydrophobic drugs. Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. From time to time many workers have claimed various rational applications of Self-emulsifying formulation...

Recent Approaches in Self Emulsifying Drug Delivery System

Self emulsifying is a topic of current interest for overcoming the formulation difficulties of drugs with poor aqueous solubility. SEDDS are isotropic mixture of oil, surfactant and co-surfactant with a unique ability to form fine oil-inwater (o/w) emulsions or micro emulsions upon mild agitation in the gastrointestinal tract which present the drug in a solubilized form, and the small size of f...

preparation and characterization of a solid self emulsifying drug delivery system (ssedds) for loratadin by extrusion-spheronization

Self Micro Emulsifying Drug Delivery System - A Capsulization

The aim of the present work is to emphasize about the importance and to make a capsule review on self micro emulsifying drug delivery system. Oral route of drug administration has been the most prominent way of drug delivery system, because of its ability to prepare the formulation in an economical way, easy to administer, does not require any specific storage condition compared with parenteral...